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What is Mohs Surgery

Mohs surgery provides the highest cure rate and smallest scar for many types of skin cancers. Depending on the diagnosis, location, and other features of your skin cancer, your doctor may recommend Mohs surgery.


Dr.Perlis performing Mohs Micrographic Surgery

This technique was named after Frederick Mohs who developed the approach in the 1930s. It involves excising the skin cancer and then evaluating 100% of the excised margin while you wait. Preparation of the skin tissue for examination under the microscope may take 45 minutes or longer. The process of excising additional skin and examining it is repeated until clear margins are confirmed. Most patients are cleared of their skin cancers in 1-3 “layers” of Mohs surgery.

After Mohs Surgery

Once the skin cancer is confirmed cleared, the resulting skin defect is repaired. Sometimes the defect may be allowed to heal on its own (second intention), while other times it must be reconstructed with sutures. If the wound requires sutures, you may be asked to follow up in 1 to 3 weeks to have the sutures removed.

After the sutures are removed, the incision is not completely healed. Your scar will continue to mature and improve for an entire year. Some patients may benefit from addition revisions or dermabrasion to optimize the final cosmetic result.

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A pain free & positive experience

Dr Perlis just performed Mohs surgery on me & made it a pain free & positive experience. He & his staff are very thorough & professional while being pleasant & caring. I will definitely refer my family & friends to this practice!!! Joyce Van Newkirk

Mohs Surgery: The Most Effective Treatment for Skin Cancer

Why Choose Keystone Dermatology Partners?

Dr. Perlis and his team are particularly skilled in Mohs surgery. He completed an internship in general surgery at the University of Pennsylvania as well as a one year Mohs fellowship through the American College of Mohs Surgery at Brown University. He and his team have successfully performed over 12,000 Mohs surgeries since he returned to the region over ten years ago.

Medical Dermatology


Dermatology is the branch of medicine that treats conditions affecting the skin, scalp, hair, and nails. As the largest organ in the body, over 3000 different diseases may affect the skin. Many times skin changes provide clues to systemic illnesses.

Some of the more common conditions in medical dermatology include:

Medical dermatology also includes treatment for less common conditions like:

  • Autoimmune connective tissue disorders
  • Blistering disorders
  • Cutaneous Vasculitides
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Skin Cancer


Skin cancer is the most common form of cancer in the world. Over five million cases of skin cancer are diagnosed in the United States each year; this is more than the number of new cases of prostate, breast, lung, and colon cancer combined. Most skin cancers are associated with ultraviolet (UV) radiation from the sun.

What skin cancer looks like depends on the type of skin cancer. The most common types of skin cancer, squamous cell carcinoma and basal cell carcinoma, may present as pink or red sores that do not heal. They sometimes itch, hurt, or bleed. Melanoma sometimes appears as a mole with several shades of brown, black, pink, purple, or red. The border may be uneven and it may change in appearance over time.

Some other less common types of skin cancer include: Merkel Cell Carcinoma, Sebaceous Carcinoma, Dermatofibrosarcoma Protuberans (DFSP) and, Atypical Fibroxanthoma (AFX).

As with most types of cancer, early diagnosis and treatment of skin cancer leads to optimal outcomes.

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Mohs Surgery


Developed by Frederic Mohs in the 1930s, the Mohs surgery technique is the most precise, advanced, and effective treatment for many types of skin cancer. Skin cancer often develops roots extending beyond the visible tumor. The Mohs technique involves surgically removing the visible skin cancer and then examining the edges (deep and lateral) under a microscope. If left over tumor is noted at one of the edges, this specific edge is re-excised and again examined under a microscope. The process is repeated until it is confirmed that all of the skin cancer has been removed.

The cure rate for Mohs surgery is up to 99% at five years. In addition, the technique maximizes the functional and cosmetic outcome following surgery by removing only the smallest amount of normal skin necessary. Furthermore, the Mohs approach is frequently the most cost-effective treatment available.

In most cases, the site of the skin cancer may be repaired immediately following Mohs surgery.

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Have Questions? Please Call (215) 390-1449